2020

Anti-androgens may protect against severe COVID-19 outcomes: results from a prospective cohort study of 77 hospitalized men.

Goren A, Wambier CG, Herrera S, McCoy J, Vaño-Galván S, Gioia F, Comeche B, Ron R, Serrano-Villar S, Ramos PM, Cadegiani FA, Kovacevic M, Tosti A, Shapiro J, Sinclair R.
J Eur Acad Dermatol Venereol. 2020 Sep 25. doi: 10.1111/jdv.16953. Online ahead of print.

The COVID-19 pandemic has disproportionally affected men.(1) Men infected with SARS-CoV-2 are more than twice as likely to be admitted to the intensive care unit (ICU).(2) This disparity in ICU admissions suggests the important role of androgens in COVID-19 severity …

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2020

Androgen Receptor Genetic Variant Predicts COVID-19 Disease Severity: A Prospective Longitudinal Study of Hospitalized COVID-19 Male Patients.

McCoy J, Wambier CG, Herrera S, Vaño-Galván S, Gioia F, Comeche B, Ron R, Serrano-Villar S, Iwasiow RM, Tayeb MA, Cadegiani FA, Mesinkovska NA, Shapiro J, Sinclair R, Goren A.
J Eur Acad Dermatol Venereol. 2020 Sep 25. doi: 10.1111/jdv.16956. Online ahead of print.

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2020

Male balding as a major risk factor for severe COVID-19: a possible role for targeting androgens and transmembrane protease serine 2 to protect vulnerable individuals

Carlos Gustavo Wambier, John McCoy, Andy Goren
J Am Acad Dermatol. 2020 Sep 11:S0190-9622(20)32600-1. doi: 10.1016/j.jaad.2020.09.015. Online ahead of print.

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2020

Androgen sensitivity in COVID-19 and antiandrogens: Prospective data are still needed.

Ianhez M, Ramos PM, Goren A, Miot HA.
Dermatol Ther. 2020 Aug 9:e14166. doi: 10.1111/dth.14166. Online ahead of print.

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2020

Are night shift workers at an increased risk for COVID-19?

Lim RK, Wambier CG, Goren A.
Med Hypotheses. 2020 Jul 29;144:110147. doi: 10.1016/j.mehy.2020.110147. Online ahead of print.

Recent data has revealed an association between coronavirus disease-19 (COVID-19) incidence and seasonally regulated androgen sensitivity. This potential relationship between SARS-CoV-2 infection and clock genes, coupled with previously reported effects of night shift work …

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2020

Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19.

Cadegiani FA, Wambier CG, Goren A.
Front Med (Lausanne). 2020 Jul 28;7:453. doi: 10.3389/fmed.2020.00453. eCollection 2020.

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2020

Spironolactone may provide protection from SARS-CoV-2: Targeting androgens, angiotensin converting enzyme 2 (ACE2), and renin-angiotensin-aldosterone system (RAAS).

Cadegiani FA, Goren A, Wambier CG.
Med Hypotheses. 2020 Jul 16;143:110112. doi: 10.1016/j.mehy.2020.110112. Online ahead of print.

In coronavirus disease-19 (COVID-19), four major factors have been correlated with worse prognosis: aging, hypertension, obesity, and exposure to androgen hormones. ...Hence, spironolactone may provide protection from SARS-CoV-2, and has sufficient plausibility to be clini …

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2020

Clock genes may drive seasonal variation in SARS-CoV-2 infectivity: are we due for a second wave of COVID-19 in the fall?

Goren A, Wambier CG, McCoy J, Shapiro J, Vaño-Galván S, Herrera S, Glode LM.
J Biol Regul Homeost Agents. 2020 Jul 16;34(4). doi: 10.23812/20-359-L-35. Online ahead of print.

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2020

Androgenetic alopecia in COVID-19: compared to age-matched epidemiologic studies and hospital outcomes with or without the Gabrin sign.

Wambier CG, Vaño-Galván S, McCoy J, Pai S, Dhurat R, Goren A.
J Am Acad Dermatol. 2020 Jul 28:S0190-9622(20)32300-8. doi: 10.1016/j.jaad.2020.07.099. Online ahead of print.

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2020

Safety Measures in Dermatology Help Minimize Spread of COVID-19.

Goren A, Rathod D, Kroumpouzos G, Jafferany M, Goldust M.
Dermatol Ther. 2020 Jun 7. doi: 10.1111/dth.13773. Online ahead of print.

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2020

Microneedling improves minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.

Sharma A, Surve R, Dhurat R, Sinclair R, Tan T, Zou Y, Müller Ramos P, Wambier C, Verner I, Kovacevic M, Goren A.
J Biol Regul Homeost Agents. 2020 Mar-Apr;34(2):659-661. doi: 10.23812/19-385-L-51.

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2020

Androgenetic Alopecia Present in the Majority of Hospitalized COVID-19 Patients - the "Gabrin sign".

Wambier CG, Vaño-Galván S, McCoy J, Gomez-Zubiaur A, Herrera S, Hermosa-Gelbard Á, Moreno-Arrones OM, Jiménez-Gómez N, González-Cantero A, Pascual PF, Segurado-Miravalles G, Shapiro J, Pérez-García B, Goren A.
J Am Acad Dermatol. 2020 May 21:S0190-9622(20)30948-8. doi: 10.1016/j.jaad.2020.05.079. Online ahead of print.

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2020

Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response.

Ramos PM, McCoy J, Wambier C, Shapiro J, Vañó-Galvan S, Sinclair R, Goren A.
J Eur Acad Dermatol Venereol. 2020 May 20. doi: 10.1111/jdv.16645. Online ahead of print.

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2020

Androgen sensitivity gateway to COVID-19 disease severity.

Wambier CG, Goren A, Vaño-Galván S, Ramos PM, Ossimetha A, Nau G, Herrera S, McCoy J.
Drug Dev Res. 2020 May 15:10.1002/ddr.21688. doi: 10.1002/ddr.21688. Online ahead of print.

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2020

Topical Alpha-1 Adrenergic Receptor Agonist Applied to the Nipple/Areola Complex Improves Female Orgasmic Function.

Goren A, McCoy J, Krychman M, Brandt L, Lah A, Lonky N.
J Womens Health (Larchmt). 2020 May 12. doi: 10.1089/jwh.2019.8188. Online ahead of print.

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2020

Allergic contact dermatitis in patients with frontal fibrosing alopecia: An international multi-center study.

Rudnicka L, Rokni GR, Lotti T, Wollina U, Fölster-Holst R, Katsambas A, Goren A, Di Lernia VG, Rathod D, Mirabi A, Ghaffari A, Rajan A, Goldust M.
Dermatol Ther. 2020 May 12:e13560. doi: 10.1111/dth.13560. Online ahead of print.

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2020

Novel yeast extract is superior to colloidal oatmeal in providing rapid itch relief.

Dhurat R, Sharma A, Surve R, McCoy J, Kovacevic M, Goren A, Tan Y, Zou Y, Goldust M, Situm M, Stanimirovic A.
J Cosmet Dermatol. 2020 May 2. doi: 10.1111/jocd.13436. Online ahead of print.

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2020

Racial Variations in COVID-19 Deaths May Be Due to Androgen Receptor Genetic Variants Associated with Prostate Cancer and Androgenetic Alopecia. Are Anti-Androgens a Potential Treatment for COVID-19?

McCoy J, Wambier CG, Vano-Galvan S, Shapiro J, Sinclair R, Müller Ramos P, Washenik K, Andrade M, Herrera S, Goren A.
J Cosmet Dermatol. 2020 Apr 25:10.1111/jocd.13455. doi: 10.1111/jocd.13455. Online ahead of print.

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2020

A preliminary observation: Male pattern hair loss among hospitalized COVID-19 patients in Spain - A potential clue to the role of androgens in COVID-19 severity.

Goren A, Vaño-Galván S, Wambier CG, McCoy J, Gomez-Zubiaur A, Moreno-Arrones OM, Shapiro J, Sinclair RD, Gold MH, Kovacevic M, Mesinkovska NA, Goldust M, Washenik K.
J Cosmet Dermatol. 2020 Apr 16. doi: 10.1111/jocd.13443. Online ahead of print.

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2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to be androgen mediated.

Wambier CG, Goren A.
J Am Acad Dermatol. 2020 Apr 10:S0190-9622(20)30608-3. doi: 10.1016/j.jaad.2020.04.032. Online ahead of print.

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2020

What does androgenetic alopecia have to do with COVID-19? An insight into a potential new therapy.

Goren A, McCoy J, Wambier CG, Vano-Galvan S, Shapiro J, Dhurat R, Washenik K, Lotti T.
Dermatol Ther. 2020 Apr 1:e13365. doi: 10.1111/dth.13365. Online ahead of print.

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2020

STAT3-mutated hyperimmunoglobulin E syndrome with perianal skin tags and erosions: A case report.

Fölster-Holst R, Kazeminejad A, Rokni GR, Lotti T, Goren A, Goldust M.
Dermatol Ther. 2020 Mar 26:e13333. doi: 10.1111/dth.13333. Online ahead of print.

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2020

Low-level laser therapy and narrative review of other treatment modalities in androgenetic alopecia.

Galadari H, Shivakumar S, Lotti T, Wollina U, Goren A, Rokni GR, Grabbe S, Goldust M.
Lasers Med Sci. 2020 Mar 11. doi: 10.1007/s10103-020-02994-4. Online ahead of print.

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2020

Erosive pustular dermatosis of the scalp: a multicentre study.

Starace M, Iorizzo M, Trüeb RM, Piccolo V, Argenziano G, Camacho FM, Gallyamova Y, Rudnicka L, Umbert I, Lyakhovitsky A, Vañó-Galván S, Goren A, Alessandrini A, Bruni F, Piraccini BM.
J Eur Acad Dermatol Venereol. 2020 Jan 18. doi: 10.1111/jdv.16211. Online ahead of print.

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2020

Yeast extract demonstrates rapid itch relief in chronic pruritus.

Zhang Y, Tan Y, Zou Y, Bulat V, Lugovic Mihic L, Kovacevic M, Lotti T, Verner I, Stanimirovic A, Situm M, Goldust M, Liu W, Vojvodic A, Goren A.
J Cosmet Dermatol. 2020 Jan 10. doi: 10.1111/jocd.13265. Online ahead of print.

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2020

Non-ablative radio frequency for the treatment of androgenetic alopecia.

Tan Y, Wei L, Zhang Y, Goren A, McCoy J, Stanimirovic A, Lotti T, Kovacevic M.
Acta Dermatovenerol Alp Pannonica Adriat. 2019 Dec;28(4):169-171.

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2020

Can we halt male androgenetic alopecia progression without antiandrogenic drugs?

Ramos PM, Santos LDN, Mesinkovska NA, Goren A, Miot HA.
Dermatol Ther. 2020 Jan;33(1):e13197. doi: 10.1111/dth.13197. Epub 2020 Jan 2.

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2020

Novel topical formulation applied to the nipple-areola complex improves female orgasm.

Krychman M, Goren A, Brandt L, McCoy J.
J Cosmet Dermatol. 2020 Feb;19(2):404-406. doi: 10.1111/jocd.13262. Epub 2019 Dec 17.

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2020

Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil treatment in Brazilian female pattern hair loss patients.

Ramos PM, Sinclair R, Miot HA, Goren A.
Dermatol Ther. 2020 Jan;33(1):e13195. doi: 10.1111/dth.13195. Epub 2019 Dec 27.

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2020

Efficacy of topical latanoprost in the treatment of eyelid vitiligo: A randomized, double-blind clinical trial study.

Nowroozpoor Dailami K, Hosseini A, Rahmatpour Rokni G, Saeedi M, Morteza-Semnani K, Sadeghi Z, Ghasemzadeh Diva SM, Goldust M, Lotti T, Vojvodic A, Goren A, Sonthalia S, Rathod D.
Dermatol Ther. 2020 Jan;33(1):e13175. doi: 10.1111/dth.13175. Epub 2019 Dec 26.

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2020

Vemurafenib and cobimetinib-induced toxic epidermal necrolysis in a patient with metastatic melanoma.

Poduje S, Brozić JM, Prkačin I, Delaš Aždajić M, Goren A.
Dermatol Ther. 2020 Jan;33(1):e13174. doi: 10.1111/dth.13174. Epub 2019 Dec 11.

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2020

The impact of short tandem repeat variation on gene expression.

Fotsing SF, Margoliash J, Wang C, Saini S, Yanicky R, Shleizer-Burko S, Goren A, Gymrek M.
Nat Genet. 2019 Nov;51(11):1652-1659. doi: 10.1038/s41588-019-0521-9. Epub 2019 Nov 1.

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2020

Oral minoxidil bio-activation by hair follicle outer root sheath cell sulfotransferase enzymes predicts clinical efficacy in female pattern hair loss.

Ramos PM, Goren A, Sinclair R, Miot HA.
J Eur Acad Dermatol Venereol. 2020 Jan;34(1):e40-e41. doi: 10.1111/jdv.15891. Epub 2019 Sep 11.

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2019

Radio Frequency in the Treatment of Androgenetic Alopecia

Goren et al.
Journal of Cosmetic Dermatology (Submitted 2019)

2019

Novel Shampoo Reduces Hair Shedding by Contracting the Arrector Pili Muscle via the Trace Amine Associate Receptor

Goren et al.
Journal of Cosmetic Dermatology (Accepted 2019)

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2019

Evaluation of the diabetogenic effect of methotrexate in psoriatic arthritis patients with metabolic syndrome, a pilot study

Dehpouri et al.
Dermatology Reports 2019; volume 11:7965

2019

MISSION IMPOSSIBLE: DERMAL DELIVERY OF GROWTH FACTORS VIA MICRONEEDLING

Dhurat R, Sharma A, Goren A, Daruwalla S, Situm M, Kovacevic M.
J.Dermatol Ther. (Accepted 2019)

2019

Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Up-Regulating Follicular Sulfotransferase Enzymes

Aseem Sharma, Andy Goren, Rachita Dhurat, Sandip Agrawal, Rodney Sinclair, Ralph Trueb, Sergio Vano-Galvan, Guangping Chen, Yamili Tan, Maja Kovacevic, Mirna Situm, John McCoy.
J.Dermatol Ther. (Accepted 2019)

2019

Identification of the Sulfotransferase Iso-Enzyme Primarily Responsible for the Bio-Activation of Topical Minoxidil

J McCoy, A Goren, T Naccarato1, M Kovacevic, M Situm, VL Skudar, T Lotti.
J Biol Regul Homeost Agents (Pending Publication).

2019

History of Vitiligo

Kovacevic Maja, Franceschi Nika, Situm Mirna, Goren Andy, Stanimirovic Andrija, Valle Yan, Lotti Torello.
Springer (Pending Publication).

2019

Platelet Rich Plasma in Androgenetic Alopecia: A Systematic Review

Lotti T., Goren A., Verner I. d’Alessio P., Franca K.
J.Dermatol Ther. (Pending Publication).

2019

Integrative Dermatology: The Microbiome in Hair Disorders

Goren A, Situm M, Kovacevic M, McCoy J, Lotti T.
Wiley (Pending Publication).

2018 November

Frontal Pattern Hair Loss Among Chinese Women is Frequently Associated with Ponytail Hairstyle

Goren A. Wei L., Yimei T., Kovacevic M., McCoy J., Lotti T.
Dermatol Ther. 2018 Nov 20:e12784. doi: 10.1111/dth.12784.

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2018 October

Low Dose Daily Aspirin Reduces Topical Minoxidil Efficacy in Androgenetic Alopecia Patients

Goren A., Sharma A., Dhurat R., Shapiro J., Sinclair R., Situm M., Kovacevic M., Skudar L V., Goldust M.,Lotti T., McCoy J.
Dermatol Ther. 2018 Nov;31(6):e12741. doi: 10.1111/dth.12741. Epub 2018 Oct 8.

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2018 July

Anterior, Frontal Congenital Triangular Alopecia, Redundancy in Therapy without Improvement; A Case Report

Goldust M, Rokni G, Sadr S, Mirabi A, Goren A, Lotti T.
J.Dermatol Ther. (Accepted July 24, 2018)

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2018 July

Minoxidil in the Treatment of Androgenetic Alopecia

Goren A., Naccarato T.
J.Dermatol Ther. (Accepted July 16, 2018)

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2018 July

Characterization of follicular minoxidil sulfotransferase activity in a cohort of pattern hair loss patients in Indian subcontinent

Jill Chitalia, MD, Rachita Dhurat, MD, Andy Goren, MD, John McCoy, PhD, Maja Kovacevic, MD, Mirna Situm, MD, Ty Naccarato, Torello Lotti, MD
J.Dermatol Ther. (Accepted July 10, 2018)

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2018 June

Controversies in the Treatment of Androgenetic Alopecia: The History of Finasteride.

Goren A, McCoy J, Situm M, Dhurat R, Krychman M, Kovacevic M, Sharma A, Bolanca Z.
J.Dermatol Ther. (Accepted June 12, 2018)

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2015

ProDrugs in Dermatology

Goren A, McCoy J, Lotti T.
European Handbook of Dermatological Treatments. 2015. ISBN 978-3-662-45139-7.